antlion

Wednesday, February 16, 2022

2B-DCK

Age: 26

Weight: 130 lbs

Dosage: 600 mg intranasal

Setting: My house

 

Preface:

So of course I was super excited when I first saw this compound on the market. This was the first brominated arylcyclohexylamine to hit the market, and its activity would help us answer some questions about the role of different halogens on the activity of ACH’s. We start at the top of the periodic table, with 2F-DCK bearing a fluorine, then Ketamine bearing a chlorine, and now 2B-DCK bearing a bromine. This clear progression down the halogen column will let us see a clear correlation between the choice of halogen and the activity of the resulting compound!

Seeing as 2F-DCK is slightly more potent than ketamine, my initial inference is that 2B-DCK would in turn be less potent than ketamine. This unfortunately proved to be the case- 2B-DCK is significantly less potent than ketamine with a shorter duration, all suggesting a lower affinity for the NMDA receptor. Perhaps that big bulky bromine just starts to get in the way of binding to the NMDA channel. It could then be inferred that this pattern holds true for other Arylcyclohexylamines, at both the 2- and 3- positions.

So the conclusion that can be drawn from this- there is a drop in activity as you substitute ACH’s with halogens, directly correlating with the bulk of that halogen, which naturally increases as you move down the periodic table. Thus the highest activity is in Fluorine compounds, followed by Chlorine, Bromine, then, presumably, Iodine. The only other reference point for this is with the PCP series, where we have 3F-PCP, 3-Cl-PCP, and one alleged report of 3-Br-PCP. 3F-PCP is significantly less potent than base PCP, and more potent than 3-Cl-PCP. 3-Br-PCP is purported to be inactive (though I dispute this claim and I think it warrants further investigation- sure 3-Br-PCP probably quite impotent and not very exciting but I would be very surprised if it were entirely inactive). Interestingly, in terms of developing compounds, chlorinated compounds seem to strike a perfect balance between dropping activity and interesting, unique effects. Ketamine is of course well renowned and well-loved worldwide and 3-Cl-PCP is one of the most fascinating dissociatives I have encountered- both are pretty impotent but the effects are interesting enough to warrant exploration. Advancing the next step down to the bromine however likely has diminishing returns.

What can I say about 2B-DCK specifically? Not much honesty. It is more painful to snort than 2F-DCK or Ketamine. Snorting 600 mg of it is just an awful experience. Rectal or intramuscular administration is probably best for this. It has a very rapid onset and a very short duration, with a peak lasting for only about half an hour and overall effects dissipating entirely in a little over 2 hours. The experience is fairly nondescript and empty, it is not particularly visual or exploratory or novel, it is an empty neutral dissociation with a bit of warmth and a hint of psychedelia on the tail end. This may be nice for people who prefer lower doses of ketamine, but as someone who always likes to shoot for the dissociative hole at high doses, this just doesn’t do it for me. I am doubtful I will revisit this compound much after this.

 

T0:00- Crystalline sample is crushed into a fine powder and cut into a big pile. I begin cutting off lines and snorting it while I am playing Chivalry: Medieval Warfare and watching The Simpsons, alternating large excruciating sweeps with smaller bumps. It is incredibly unpleasant to snort, it stings a good bit more than other ketamine analogues I’ve tried and tastes pretty dreadful. Overall, it took me about 20 minutes to take it all down. Maybe I’m a wimp, I would prefer not to do this anymore though.

 

T0:15- Still working down the pile. This is the onset of effects- a soft dizziness, numbness in my fingers, a sensation of my body becoming floppy and heavy and difficult to control. The game is making less and less sense to me and my fine motor coordination is becoming increasingly stunted, making play quite difficult. The Simpsons is becoming an annoying stimulus, hard to pay attention to, but thankfully the episode is ending.

 

T0:20- Finished snorting the pile. My nose doesn’t feel too good; I wash it with a saline rinse. I feel like I have rapidly dropped into a hole, that it slinked up and ambushed me before I could even discern what was happening. It tugs at me, I am moving so slowly, it is like a dream where I get in a fight but all my movements are gelatinous and inhibited as though I am under water. I close out of the game and climb up onto the couch and flop down, content not to move at all.

There is a rush in how sudden this is, but at the same time, it is something warm, smooth, and gentle, like I have dropped into a hot tub, sleek and streamlined, leaving no splash in my wake. I would generally characterize Ketamine and 2F-DCK as being “cold”, lacking an internal energy. This is a warm sensation though, burning quietly like a glowing ember, passing the soft warmth of the lapping of a tropical sea through my limbs and into my extremities, turning them into a body-temperature jelly. The light and energy is quiet, it is like I am sitting on a throne of low flames, their energy imparting haloes of a golden-orange glow around me, this is nothing electric or stimulating, just simply warm.

The world feels blurry, wavy and disconnected, a function of warbling heat waves more so than the actual air carrying the light to my eyes. There is a sudden sense of this world I’m in being fake and virtual, and there is a lax resignation in the drug to just not even care about that fact at all or give it any regard. I am content to just lie here and space out and exist in this fast and novel sensation of being numb and gooey, the sense of motion when I am sitting very still, like my essence is lazily spinning down a vast drain. It is hard to read or write, my notes are near-incomprehensible with typos and gibberish, the letters on my screen border on being empty meaningless symbols that my brain has disconnected with any literacy I have ever learned. Visuals begin to appear, they are cubic and quadrilateral, patterned squares, bordered by patterns, reminiscent of the Thwomp of the Mario franchise or the Portal’s Weighted Companion Cube, cast in a translucent violet and blue.

 

T0:29- I am so dissed, I feel like a circle, my teeth are numb and I sense that I am on the verge of just drooling on myself. It feels silly to be in such a state- and yet, I can be aware of how silly it feels. Despite the intense physical sensation, my mind feels fairly lucid, I can make perfect sense of how off-base I am. I decide to lie down and put in my headphones and listen to music in the dark: Oneohtrix Point Never’s ‘R Plus Seven’.

 

T0:37- I get bored after a little under ten minutes in that I can start to feel my body again and in that I already feel like I am coming down from the experience. It is hard to focus on the intensity of a dissociative experience when I can still feel my body. Perhaps I should have attempted this part of the experience 15 minutes ago.

What I can discern of the hole is a grimy noir, dark and rain soaked and lit by neon and streetlights, in constant and steady motion. Wet pavement reflecting the ambient buzz of colored lights cutting through the gloom, red and orange and pink. It is a hollow space that echoes with drips and drops like a great yawning cavern, it is graced by a warm wind and dizzying foggy sky. I traverse it in a steady line like I am riding a train or a streetcar. The world ambles by at a constant pace, never stopping or jerking or twisting or turning or changing directions, just stillness in motion, slow, smooth motion.

The closed eyed visual space is vague and none too intricate. Light dancing on basic geometric forms, the same squares and cubes that vaguely presented with my eyes open as well. There are no intricate patterns, nothing more complex than right angles and blocks of color, stacked and arranged in regular grids. It’s not particularly engaging or interesting. My mind is too lucid, I cannot lose myself in the whimsy and wonder of this experience, all I can think about is how I can still move my body freely if I want to, freely enter and control it, that same physical body connected to the same physical world where all my physical world obligations and worries lied, none of that wondrous liberatory dissociation I am always in such ravenous pursuit of. Maybe I would find that at a higher dose, but I have no interest in taking any more, in snorting that much more powder just for the off-chance of turning a dull experience into something revelatory. I wonder if there is anything revelatory to be found here at all. I feel bounded, trapped within the very real and visible limits of this drug, none of the bottomless potential energy that some dissociatives can present. I unplug my headphones and just sit in the dark in silence. There is some warbling and phasing of ambient noises, but it is slight and easy to ignore. All I can do is just sit here, space out, resign myself to blankness and emptiness as the closest I can get to some dissociative escapism. The faint visuals are cast on the walls, aimlessly and quietly drifting down like cascades of water.

Despite the lucidity and being aware of my body, I am still quite incapacitated and uncoordinated. Getting up, walking around, moving, are all exceptionally difficult. My limbs aren’t going where I want them too, my sense of proprioception is completely out of whack. There is some dissociative heft to this compound, even if it is only at high doses.

 

T0:43- I break into fits of sneezing, I find that I am rapidly regaining control of my motor functions. Perhaps the shock of sneezing so much has really thrust me back into my body. I am still appreciably fuzzy and floppy, but the experience is well beyond the peak now. I am a leaf, slowly drifting and flitting to the ground. There are new visuals on my ceiling, presenting with the same reserved clarity that the visuals were before, ripples and streamers, in fluid and graceful segmented motion like swimming Polychaetes. While the visual aspect has remained the same, the physical dissociation decreases substantially with each passing moment.

 

T1:04- Feeling more and more grounded, edging closer to sobriety. My motor control has mostly returned, the only physical sensation that remains is a lingering sense of lightheadedness and numbness in my extremities.

 

T1:17- Dizzy and mostly down, there is a little bit of stimulation remaining now that most of the dissociative remnants have blown away in the wind, presenting in a curiosity and a desire to go about reading things. Little bits and pieces of information I read on social media become sticking points for internet holes, reading Wikipedia pages and news articles.

 

T1:40- There is a nice afterglow here. All sense of dissociation is purely cognitive at this point. I would describe the headspace as bordering on psychedelic, more so than ketamine or 2F-DCK, it is that sense of free flow and association between thoughts, of increased desire to read and take in information, of moments sticking in my memory more. There is a bit of euphoria to this.

 

T2:30- Fully back to baseline.

 

Conclusion: This drug is in theory pretty interesting, but in practice it presented some fairly boring trials that I feel would’ve been better spent on some other dissociative. It is not particularly fascinating or exciting, but it definitely is a dissociative with a good bit of heft, for the time it lasts. Consuming it is a pain, I am content to never have to snort that amount of powder again. I wonder if my nasal cavities became saturated after a point, putting an upper limit on how much of this drug I can take. Perhaps I should use both nostrils. I may at the very least try it orally at some point in the future- 2F-DCK has good oral bioavailability. If there is a clear correlation in effects with heavier halogens though, I am doubtful 2B-DCK will have any oral bioavailability, considering how little ketamine has. Rectal administration is probably more worthwhile than intranasal too.

The experience itself is lackluster. The onset is rapid, the peak is under an hour, and the experience has dissipated entirely in less than 3 hours. It is a heavy empty dissociation similar to other ketamine analogues, with a nice rush on the comeup. There is a warmth to the quality of this one- interesting, though not especially remarkable. There is some visual character, though the visuals are faint. They are cubic and geometric and fairly simple, cast in dull warm tones accented with deep blues. The headspace is remarkably lucid, more than an equivalent dose of 2F-DCK or Ketamine would be. Motor skills were thoroughly incapacitated at the peak, though there was never a full sense of detachment from my body. Thought processes remained fairly normal throughout, though perhaps with a bit of underlying psychedelic stimulation. There is something there in terms of intensity- something had me satisfied enough that I didn’t even feel the need to touch cannabis during the experience. I’m glad I got to try this drug and it was interesting for its relation to similar compounds, though I don’t see much purpose in exploring it further. If I want something short and hefty I will have its siblings that bear lighter halogens