2C-I

Age: 20

Weight: 120 lbs

Dosage: 18 mg 2C-I oral in gel cap

Setting: All around park and cool rock and schuylkill trail and my friend's house

T0:00-Dose while on the bus to my favorite tripping spot. Other people don’t seem to notice me conspicuously just pop a pill.

T0:30-Have arrived at my spot, not really feeling much yet, a slight stimulation in my body.

T0:45-First visuals begin to present in slight color enhancement and faint transformation of mottled surfaces to patterns in my periphery. I have decided to explore the woods near my spot and have discovered an incredible place. The forest is littered with fire pits and encampments, and part of it has a large stone wall on a cliff with windows and stairs down to the park below. It’s like a castle! There is a large boulder that I can climb and sun myself on too, and its really cool because a really busy road cuts through the boulder with a tunnel. Ascending this wooded hill, I reach the summit, a large open space with logs to sit on and a large peace sign made of vines and painted and tied to a tree. All of this seems like ritual spaces, but from what I’ve heard hippies just gather there and do drum circles once a week.

T1:00-I run around the forest because I am suddenly so stimulated and full of energy. If I stop moving my legs feel twitchy and itchy and restless. Some nausea is setting in, but I took many measures against it (This being monitoring my diet for the past 24 hours, taking a trace mineral preload, drinking ginger ale and taking ginger extract supplements, immodium, tums, and pepto bismal tablets). I perhaps would be in more pain had I not, and maybe even vomited.  I manage to sit down and smoke a bowl on the summit of the hill however. The weed feels nice, it feels like it leeches into my body and numbs the nausea and restlessness. I lie down and stare at the sky and listen to music. The patterns that form from the clouds are large and colorful and not very intricate. I close my eyes and the CEV’s are also somewhat faint, but much more intricately patterned.

T1:15-Open eyed visuals becoming more apparent. The dirt in front of me begins to form patterns out of mirroring itself, when suddenly it all gets interrupted by the patterns melting and warping. Soon my entire field of vision is mirroring, warping, bulging, melting. I fall sort of into trances when this happens, although I can snap myself out of it and restore a more functional and less altered field of vision. Leaves and trees multiply and fractalize to look like snowflakes.

T1:40-I decide to leave the forest after running around some more. I feel very focused, it is the sorted boosted mental aptitude I feel when I am on acid. I also feel like I have superior proprioception. I see now why people often sell this 2C as “An LSD-like experience”. It feels very similar, although more stimulating, and the visuals have a different nature. They seem more synthetic, with less pareidolia or organically blossoming/flowing shapes and patterns. To reach the trail that I want to walk on, I have to climb down that boulder. My sense of balance and my control over my limbs feels vastly superior to normal, and I am able to more or less run down a nearly vertical cliff using only my feet, with my hands in my pockets.

T2:20-I feel such a sense of euphoria and whimsy as I walk around. There are lots of people running/biking/walking the same trail, and I get this sense that interacting with anyone would be very difficult and awkward in this state.  I am outside though, I have access to the great sky and beautiful plants and fresh air all around me, everything is seen through a fisheye lens with distortions on the periphery and everything is colorful and beautiful. A friend invited me to a party later that night and I decide whether or not I’m going to go. I branch off the trail to a cool smoke spot overlooking the river. While there I see a goose. I end up staring at it for a good 15 minutes, just utterly fascinated by this living breathing animal in front of me. The way it preens its feathers, the way it bent its neck and moved its head as if trying to communicate with me, the expression on its face, it was all so fascinating.

T2:50-The sun is setting. I decide to walk to my friend’s house. The walk there is pretty long, through a large residential area of the city. There is nothing to note, I felt pretty light and stimulated still, with the same spring in my step and the same control over my limbs.

T3:20-I arrive at their house. I am greeted by one of their housemates who sells psychedelics. There are a lot of people there, many of whom I only very vaguely know. It’s kinda overwhelming. Especially the transition from being in the open inside to a very crowded inside. It feels like the room dissolves into patterns and collapses in on me. I quickly shelter with their housemate because she definitely understands what sorta experience I’m having. I am able to anchor myself and get comfortable. Eventually, I smoke a bowl on the roof.

T3:40-My girlfriend arrives. I have never tripped this hard around her before. I quickly anchor to her, as she is in the midst of the most crowded part of the house. Everything is colorful, colors dance around my head, they dance around my vision. She says I seem spacey, and I do feel spacey. I feel like I am burning out and powering down, but it is a nice colorfully decorated ride down.

T4:00-I talk to some old friends I haven’t seen in a while. I feel less socially awkward, and I am given the opportunity to draw on a large piece of wood downstairs. I occupy myself with this for a while and don’t even notice myself coming down.

T6:00-I smoke some more and it kicks things back up slightly, at least the body high, visuals and euphoric aspect, not so much the psychedelic state of mind. I watch an old friend’s band play, it’s very emotionally charged music and watching it be performed is a very beautiful experience. I enjoy it thoroughly.

T9:00-The party goes on. I would say I’m back to baseline now.

Conclusion: 2C-I has been sold under the line “It’s a lot like acid” and I can see why. In terms of headspace and physical effects, it is very similar, although it is more stimulating, and although similar the body high leans more towards other 2Cs. The visuals are also more like the other 2C’s, being very synthetic. For me, LSD’s visuals are a coalescence of organic and synthetic, while this was more purely synthetic. At this dose I was also fairly lucid the entire time, I could operate my phone. The visuals were a great deal of fun though. Also euphoria presented. Hard to tell if that was from set/setting because this is my only time taking it, although I have a hunch that this drug has a great euphoric aspect, also contributing to it being sold as something similar to MDMA too. Overall I would say this drug is great, I want to test it to see how much bodyload it creates without my precautions, and if it is benign enough with respect to that and with respect to headspace at higher doses, it might make its way into my toolkit for making combinations, likely for situations requiring stimulation and heightened physical control.

2C-B + 2C-C + Ephenidine ++ Ketamine

(This one has been published by Erowid!!!!)

Age:20

Weight-120 lbs

Dosage:

12 mg 2C-B oral in gel cap

25 mg 2C-C oral in gel cap

100 mg Ephenidine oral in gel cap

~180 mg Ketamine Intranasal

Setting: Union transfer, around philly, my apartment

T0:00-We are going to an electronic music show (Oneohtrix point never more specifically). I had prepared a party pill of the Ephenidine, 2C-B, and 2C-C, mixed into a gel cap with ginger extract to relieve nausea. I take it as we walk to the venue from the subway. I had ingested a weed edible about 20 minutes earlier too.

T0:30-The first set has begun, it is an interesting eclectic experimental mix featuring a lot of sampling. I was pretty spaced out for the majority of this however. It was a kinda dull ambient high coming from the edible and coming out of an eagerness for my trip to kick in.

T0:50-First notes. Feel some nausea, getting slight visual distortions in dark places. I begin to realize that I may have timed this wrong, that I won’t feel as altered as I want until after the show ends, that this comeup is taking too long and I should’ve dosed earlier. I am stressed out, and I feel as though this stress is dampening the trip. I need to close my eyes, breathe deeply, be calm and focus,

T1:10-The first set has ended, the lights are up and I’m just awkwardly standing around. I go out into the lobby and sit on a windowsill and awkwardly sit around. I feel awkward and out of place, the trip is definitely kicking in now and I am just extremely mindful of my presence in the room and the space I take up. Patterns are beginning to appear, but visual distortions and warping are limited to my peripheral vision. I feel warm and tingly, with a pleasant warm dissociative numbness. I am still definitely not tripping as hard as I want to be though.

T1:40-Oneohtrix point never comes on. This music is hard to describe, honestly just go listen to it when you get the chance it’s pretty dope, most of this experiment came off his new album “Garden of Delete”. This music is extremely surreal, like about as surreal as music can get. It is perfect for a mix of psychedelics and dissociatives, in the way that it too is a storm of fragmented and altered pieces of reality, it captures that chaos in its wild sounds. This is so cool. I don’t know what much to say about the length of this set other than it was a spectacular and extremely enjoyable experience. On screens they had visual displays, these mostly consisted of very surreal animations by Nate Boyce. Definitely check these out. This entire experience resonated heavily with past DXM use, in its surreality laced with a fundamental discomfort. The animations actually resembled some of the closed eye visuals I had gotten from DXM, almost verbatim. Honestly if I were on DXM at the time I would’ve thought some broken alternate universe was trying to communicate with me. But I felt very properly stimulated by the experience, the sound was a physical object that I could feel battering my flesh. The lights and visuals danced in circles with the splattered psychedelia of my mind. I felt so fried and so content to just be standing still, melting into the ground, being a pillar of salt.

T2:40-It’s over! I go wait in the lobby and realize I am still tripping balls. There are colorful patterns melding with every surface, things are shifting out of perspective and warping. I feel almost lost. But its okay and I am okay. I manage to weave through a strange crowd of warped looking inhuman figures that swarmed around me like a river of shadows. I meet up with my comrades who I came here with. I entertain the idea of walking home because I feel so great right now. The ephenidine has touched my limbs in the sense of making them feel weightless, but no to the point where I get the noodly-leggedness of other dissociatives that would make me stumble around. So my legs feel almost superpowered, I would be stoked to walk home. The others with me don’t seem as enthusiastic though, and my one friend who was on 2C-E seemed somewhat jarred and eager to return to my house, so I led the group there.  

T3:00-We return to my house. I’m going decently hard and we sit around and smoke weed. My aforementioned friend pulls out some ketamine that he and another person with us were hitting all night. He seems somewhat anxious, and happy to indulge in the familiarity of ketamine in a more comfortable space than a music show. He cuts up 2 big lines and takes 1 and a half of them down and generously leaves the rest to me and a friend. He leaves soon after.

T3:40-My friend and I have nothing else to do for the rest of the night. We inhale the ketamine and run downstairs like eager children on Christmas morning. We have a great activity planned. I have the album “wander / wonder” by balam acab on vinyl and so we turn all the lights off, cuddle up on the couches, and spin it on the record player. If you don’t know this album I would describe it as the sounds great pulsing glowing deep sea creatures make. Lots of heavy base and water samples mixed with pitched up vocals. Immediately I feel my body fade, as if someone replaced my bones with conveyor belts and let my essence slough off. We are snuggled with blankets on the couch, and I feel like I am on an adventure, I feel like I am diving into the ocean and swimming about in its depths. I feel weightless, the entire room comes off as an endless blue void. I open my eyes and can make out nothing in the darkness, red and blue patterns fill my vision. The world looks 2-dimensional, and everything looks/feels like a cartoon.

 T4:20-Wow that was cool as hell. The album has ended and the lights are up. My one friend leaves and the other sleeps over. He spins one more record, my favorite one. I have that wonderful feeling I get from coming down on psychedelics, where my mind feels sharpened, I feel wittier and more articulate. I dance to the music which is something I rarely ever do but the ketamine has my limbs feeling nice. I go to bed about an hour later.

Conclusion: My intent this night was to sort of manufacture a specific feeling or state of mind to glean maximal enjoyment from the music performance in a multisensory experience. I feel like I did well, I concocted the right combination of chemicals to get the effects I wanted. I mostly added 2C-B to counter the sedation of the 2C-C (plus how buzzy they are in synchronicity, good for being up and out and about), they both produce wonderful visuals in their own right however. Ephenidine is a relatively lucid and colorful psychedelic dissociative + being a mild stimulant. This made the music into a synesthetic assault with sound, and It was beautiful and wonderful. I wasn't too far altered to feel stressed out or unsafe or out of control which was nice, and also paramount. Though the doses were maybe a little lower than I would've liked, the low doses I took were an essential measure to assure I could manage myself in public. and iiii did.

2C-C + 2C-B

Age: 20

Weight: 120 lbs

Dosage: 40 mg 2C-C oral in a gel cap, 25 mg 2C-B oral in a gel cap

Setting: My apartment

T-3:45-I went to the corner store to get ginger ale. I was wearing a new shirt, it was a Malaysian soccer jersey. It was loaded with static that wouldn’t go away no matter what I tried. It stuck to me, and wearing it made me feel like I was buzzing. At the corner store, some pop song in Spanish was playing very loudly. The refrain had the word “electrico!” featuring prominently. This little detail will become relevant later on……

T-3:30-I did deschloroketamine earlier in the day. It was a powerful experience, but I won’t go into it too much because that’s not the focus of the trip. It was supremely introspective, in an emotionally neutral way. It was sedating as deschloroketamine is often. I mostly just flopped around on my bed and felt like I was in big dissociative river rapids. (Also I did 10 mg of 3-MeO-PCP the previous night. I woke up on a slight afterglow from that)

T0:00-I had mostly come down from the deschloroketamine. It typically has a long sedating afterglow and I was feeling that, with just the slightest numbness in my extremities. I figured now was the time to dose. I took the capsules together with ginger ale. I went downstairs to hang out with my roommates on the comeup.

T0:20-Already starting to have visuals, with very bright patterns appearing on the walls, they are demandingly bright like neon lights. But they are 2 dimensional and a nice adornment to my world. Mentally I just feel a bit floaty and high, not anything notably psychedelic. Nausea touches in, but it’s not nearly as bad as it’s been with other drugs, very manageable. I light up a blunt eventually.

T0:50-I only finished half of the blunt. Thing were getting intense, and I realized that I didn’t want to drive it too far. The visuals have picked up very very hard. The world is beginning to distort around me, it feels like the very fabric of reality has rolled in multicolored paint and telescoped in on itself. The edges of objects begin to dismantle into colorful fractals and drift away. Everything is overlaid by repeating patterns in swirling prismatic colors, all of them seem to be formed in some sort of sequence or mathematical harmony. They look like strings of diamonds and other forms, dancing and swirling and dragging my field of vision along with them. The room warps and melts and twists in response to the actions of these forms, truly expelling me from any shred of this reality. My roommates’ conversation becomes utterly surreal and incomprehensible. These strange beings whose form has become colorful and amorphous are projecting sound waves into the abyss of the air, firing off a cannon of voice, the projectile disintegrating amongst the crushing weight of this strange world. I decide I cannot really be around people, it has gotten too strange, when voices become gibberish that’s usually a good sign that I’m tripping so hard that I can really only be alone. My sense of body I wavy and unstable, I am walking like I am on a rocking boat (it’s like a dissociative walk). I float up to my room.

T1:00-I am up in my room. I attempt to operate my laptop, it’s very difficult when the screen is shaped like a melting orb covered in rainbow faces. It feels like I am radiating concentric fields of energy that disturb and distort my surroundings, making things bend and warp and bleed colors. It is as though fractals and patterns are oozing from the walls, and being cast into the chaos of the swirling air.

I close my eyes and this is where I get swamped. Immediately I can feel my body turn to waves, I can feel it ripple on the concentric fields of my mind. Visually there are various sharply angled patterns that are multiplying and repeating at an impossibly fast rate, multiplying so fast it would not be perceivable or conceivable to a sober mind. These overwhelm me, wash over my like waves, they feel electric, it feels like my entire existence is buzzing with electricity. The physical effects are more or less juts turning into a buzzing medium for a constant flow of electricity.

Imagine you pluck a taut wire, it vibrates and bounces back and forth, at first in large waves, but slowly the waves shrink, slowly it loses momentum and vibrates slower and slower until it stops. Now imagine that when you pluck it, it does not reduce in frequency. It instead vibrates faster, and the size of its vibration grows even larger. That is what this trip felt like. It felt like I was a wire being plucked, and I was vibrating out of control into oblivion. I was destroyed.

Mentally, it was very hard to comprehend this state. This was the most vibrate-y I had ever felt from any drug, this was the stronger buzzing effect I had felt. I didn’t know what to think of it, the visuals and other sensory effects were overwhelming. I couldn’t put music on, it got too distorted and that freaked me out. Instead, the ambient noise around me repeated like a sound glitch and trailed off into oblivion. All of this sensory distortion could only be processed by my brain as being “very strange”, and I was cast into a stupor and confusion. I felt mentally lost, I was happy I was in a safe place, but it felt like my cognition was being shocked by arcs of lightning, searing and sizzling it. It was like an electric massage on my brain, lightning bolts striking from the clouds of my skull and crackling across my brain. Remember the shirt I mentioned earlier, and the song in the corner store? Everything was electric themed today, there was electricity in the air. Odd coincidence.

T1:30-Eventually, I let the waves completely consume me, and found myself far away. I was completely dissociated now, I had finally truly vibrated into the void. This new existence was in constant motion, and constant repetition and self-replication. It was visually stunning, incredibly intricate and colorful forms trailing off into nothing, appearing and disappearing at a rate that my sober mind could surely not follow. I felt like I was being blasted down tunnels, that I was riding waves of fractals up and down, that I was being tossed about at the mercy of these unknown electric forces. I also was granted the pleasure of what I would zealously label as entity contact. I eventually felt like I came to a junction of this realm. Buzzing forms would come and pluck my form, mock me and jostle me, buzz around me, it was a hazing for a stranger to this realm. They were indescribable within any sensory parameters, just imagine sentient vibrations I guess? (and not that hippie “we’re all vibrations dudeeee” stuff, this was just very direct and literal ripples in this reality) They swirled and danced, dragging shreds of this reality with them, turning this junction into an incredible disorder of forms and spaces and vibrations. Eventually, like gravity, the forms swirled together at the center. There stood a grand totem built of utterly discordant forms. Suddenly, this too felt sentient, and as I acknowledged it, it felt as though our consciousness blended into one. I was suddenly this totem, something revered and respected by the living vibrations. They stopped their mockery. I did not feel any sense of power however, I could not manipulate this realm, merely command the respect of its inhabitants. I was simply a disembodied voice vibrating within some unknowable object.

T2:20-I’m down enough to interact with people. My original plan for the night was to trip with my roommate and play videogame together. He was on acid at the moment. But we both retired to our rooms instead. I figured since I was past the peak I could go hang out. So I go downstairs and watch my other roommate play shadow of the colossus. This is my favorite game, and watching it brings back intense nostalgia. I love this. I feel the deeper and more eloquent thought of the comedown of trips. I appreciate younger me for liking this game, I think younger me is cool for playing it so much. Weird narcissism. This state becomes most prominent about an hour after the peak, I was currently post peak and the visuals were raging hard. Interlocking intricate patterns were on everything, flashing in blue and pink. I still feel like I am buzzing, but much lighter, I feel like a vibrating phone.

T3:00-The visuals remain, albeit lighter and less prominent. They simply adorn my existence. I feel like I have just been shocked and burnt. I feel burnt out, I feel like I vibrated so hard that it’s left a residual sort of fuzziness in my body. It is centered in my skull, in the middle of my brain. I feel literally shaken. That was cool and interesting.

T6:00-I am mostly down now, the burnt out buzzed out feeling remains until I go to sleep.

This trip was electric!!!!!!!

LSD ++ Ephenidine + 2C-C (Intranasal)

Age:20

Weight: 120 lbs

Dosage:

3 tabs LSD sublingual

70 mg Ephenidine oral in gel cap

25 mg 2C-C Intranasal
Setting: My apartment

T0:00-Administered 3 tabs of LSD and took a shower.

T0:30-Exit shower, feel immaculate and clean, purified and comfortable. I walk into my cozy room, lit up by the afternoon sun, the beams of light manifest in the smoky atmosphere from the incense I burnt. A blunt I rolled beforehand awaits me on my desk.

T0:40-Slowly builds. Based on my history with acid (usually I would take 3 and it would be very manageable and malleable), I figured this would be a light experience that I would accent with other substances, a sort of background trip to be built upon. A friend comes over and doses. He and my roommate and I are relaxing in my room, I decide to light up that blunt.

T0:50-Holy shit that blunt. My roommate and friend are hanging out talking. I eventually go silent and lie back on my bed. I am rising so heavily I cannot really communicate at all. I close my eyes and am greeted by an explosive well of fractals and blooming forms. It beckons me, but I cannot dive in while sharing the space with others, that would make me feel vulnerable and reckless.  But this is getting out of hand. Auditory hallucinations begin to chew their voices apart and I can feel the gentle breeze at the edge of a raging storm of thought loops and ego death. The breeze carries a flurry of open eyed visuals, patterns and fractals relentlessly playing themselves on my field of vision. This is going to be big. Something is going to happen. I feel very small as the room stretches away from me, obliterating all depth perception, perspective and sense of scale. I can’t do this anymore. I manage to piece together the words and kindly ask them to leave me alone for a bit. Both of them are very experienced with psychedelics/familiar with my penchant for doing them alone, so they politely comply and go downstairs to watch a movie.

T1:10-It seems another instance of no accurate timestamps for like an hour and a half, as time is violently dismantled. Alone at last, I let the storm wash over me. I lie down on my bed and close my eyes and bam-Imagine a frail house getting blasted by the winds of a hurricane, wood and debris flying off, until at last the rotting beams snap and the entire structure gets flattened, mowed over by the wrath of air being flung about. That was me, I was flattened and mowed over by a psychedelic gale. The wind comes in chunks, each one resonating and vibrating my bones and essence as it strikes me. Each strike, I come apart more and more, I vibrate at higher frequencies until my being is shredded, split, utterly dismantled and mangled. I love acid because I usually feel in control, I am euphoric and I feel enhanced by psychedelic magic. This time however, I am at the mercy of this amorphous storm.

I begin to realize what I’ve gotten myself into. The original plan was to take acid, then 2C-C, and then chill out on the couch with my friends. That wasn’t going to happen, that wasn’t going to happen for a while. I could barely stand up. My entire field of vision more or less melted and warped, it was familiar and undistinguishable. My short term memory began to short out as time got utterly abstracted.

I tried to throw on some calming music. Ho boy. This is where things got really freaky. The sounds of familiar sounds had become alien and unrecognizable. It was like the sounds were dissected, every layer was split apart and run through a tangle of distortion. Soon things began to get creepy. The songs would begin to slow down and speed up, seemingly randomly, with the accompanying drop/rise in pitch. This was it, this was my reality breaking apart, I was truly sensing a rift in reality stronger than any I had ever done. I feel like I broke everything. I felt like this was the big one, this was the trip that would end in severe consequences due to its sheer power. The world as I knew it cracked open, and there was doubt in my mind as to whether it would ever come back. But whatever, just ride it out. I felt like I had damaged reality.

I put on very minimalist calming slow ambient music, it helped a bit (how I managed to operate my computer is beyond me). This great sense of dread and foreboding overcame me. It was the sort of fear when you are exploring an abandoned building, and a chill runs down your spine, when you hear a sound in the distance when you think you are alone. I felt like I had hacked into reality, split it open to reveal the inner workings and the mechanisms that drive it. I suppose I could make this analogous somehow to some scientific definition of “dimensions”, just iterations of space packaged within each other, each one influenced by the one it was within. Okay, I don’t know if that’s actually how dimensions are defined, but with my limited knowledge on the subject that’s the impression I have.

The fear however, came from the fact that something did not want me doing that. This something was not even a “thing” it was beyond our definitions, it was an essence of darkness and malice that could not even exist in our world, for it was beyond existence. Perhaps it was not malicious, but merely protective. However it felt, it did not want me here at all. I felt like punishment was incoming, that some strange interdimensional police would come and trap me in some asphodelic eternity.

If I could give a sensory aspect to this, the visual space of this shattered reality was onion shaped and bulging pulsing forms, vibrating with the overwhelming psychedelic wind in a gelatinous aether. It was here that I realized how much of a role acid played in my “dextroverse” (LSD+DXM+DPH+some tryptamine) experiences, which I had in the past mostly attributed to the DXM. The sounds were… okay imagine a drumbeat, a deep bass that reverberated with a wicked splash, getting warped repeatedly, its edges softening each time, its tone dropping each time. This beat was the sound of me being chewed apart by the acid, it was the steady sound of reality methodically breaking apart. I cannot place why, but this was so fundamentally disturbing, the sensory aspect of this has given me a newfound respect and deep deep fear of the dark and undisturbed depths of LSD.

I could pull myself out briefly. In one instance the concentric rainbows on my computer screen warped into spider like creatures. In another I picked up pen and paper and began to draw. It anchored me and kept me from accidentally falling into the forbidden space I had been delving into. I felt like I was being exposed to so much information, that this rift was leaking forbidden knowledge into my head. I could not write this, but at the time I felt like drawing it was a way of encoding and recording it. Of course the drawing failed to convey any of this information once I was in a sober state. Other times of brief lucidity, I wanted to take a benzo, I wanted to tap out and hit the eject button. Oddly enough, I was enjoying this deep disturbance, it was like a horror movie, but I had pals over and wasn’t prepared for /in the mood for a trip this intense. If I had planned for this, this could probably have gone much deeper, but I had to restrain my brain.

T2:25-Okay. Okay, the storm is passing, the winds are slowing. I am still tripping extremely hard, but at last the great well of forbidden knowledge was closed to me, and I was no longer at risk of a true crisis of my reality. I decided to go downstairs. My friends were watching Animatrix. I sat and watched with them, saying nothing as I tried to gently ride and navigate the comedown. The matrix… oh boy what a wrong thing to watch after my experience. The concept of something operating under our reality that did not want to be found out… it was truly hammered home. It was kinda scary, but I was out of the woods now, so it wasn’t too bad. Very intense to witness though.

T3:10-The movie ends. We put on another one, an anime movie called ninja scroll. Some attempts at conversation are made but I am too jarred to maintain them. Ninja scroll is fucking sweet, just beautiful animation, cool action and strange characters with cool powers. It plays out like a videogame, just a dude fighting a series of powerful foes. But it was so cool and well animated. I noticed I wasn’t viewing it super analytically like I typically do with media while on/coming down from acid.

T3:40-Another friend comes over. I am still jarred and tripping hard, but I feel highly functional compared to how I was before. We hang out and draw stuff for a while. Lots of kush gets smoked. We go back to my room and hang out there, drawing etc. It’s fun, I begin to articulate my experience to my friends and we have nice conversation. My friend who was coming down from his trip decided to try deschloroketamine, so I shared a dose. I personally popped a cap of 70 mg ephenidine. I was in a more comfortable and better state now, so I figured why not, ephenidine was never too taxing on reality and very manageable. 70 mg is a pretty low dose anyways. We hang out more and talk more about all sorts of things, I feel a bit of numbness as I come up.

T5:40-The ephenidine begins to peak as numbness and dizziness, the typical “dissociative walk” and a sort of brightening of visuals. Very mild. My friends go downstairs to play videogames. I tell them I’ll join them in a bit, because I wanna ramp things up. I decide to try insufflating 2C-C. I am aware that I don’t wanna go back too far again, so I cut out 25 mg and put it in a line. The powder is fluffy and does not need to be crushed. I am kinda scared because it’s a large volume of powder. I get something to bite down on. The horrific pain of snorting 2C’s barrels in full force, the feeling of snorting glass or getting shot in the face with an arrow. I am in so much pain. I am immobilized. After about 5 minutes I go downstairs, I am still in immense pain but I feel like I can interact with people at least. The pain persists for about another 20 minutes, longer than my experiences with 2C-B, though this might be because of the volume of powder. The drip is another sort of hell, making me feel as though I have a horrendous sore throat, with awful bitter flavor.

T6:00-I am okay now. This is sweet. I am couchlocked and its so pleasant, I am buzzing and oozing waves of euphoria, everything is so colorful and bright patterns appear on everything. I love it, this is the desired effect, this is great. I am lucid and clearheaded and can interact with people perfectly. This is not exploration, simply augmentation of my reality. I enjoy it a lot.

T8:00-People have left mostly. I am feeling pretty altered still and go to 7/11 with my friends. The night feels like a magical adventure, a colorful expedition with childlike wonder. The ephenidine adds momentum to every step, the 2C-C buries the world in colors. I am so eloquent and articulate, I feel like my mind and intelligence have been enhanced tenfold. I can piece together ideas perfectly, I can form insightful associations and respond quickly and efficiently. This is great, I take advantage of this to talk about all sortsa stuff with my roommates. We get home and play super smash bros. and I am a lot better at it than when in any state. This is a perfect combination of states and subtsances, I have truly augmented myself as a human.

T9:00-Everyone else has gone to bed. I shower and think about how cool this feels. I decide to try and take advantage of this state and meditate on all sorts of things. It seems this intelligence only works when one is not aware of it however, it is odd like manual breathing. It’s will only provide me with insight and eloquence if I let it flow naturally, if I let it naturally weasel its way into my thoughts and experiences. I get out of the shower and excitedly write this piece before going to bed, feeling cleansed and mentally satiated.

Conclusion-

Wowee. This was the most intense LSD experience I have ever had, if not one of the most intense drug experiences I have ever had. It would’ve definitely been that if I let myself sink into it, if I had not restrained myself for the purpose of being social. But even with restraint, this trip was bursting at the seams, this was intensity and revelation of unimaginable powers and realms. I have a newfound respect for LSD, if not a terrible fear of its unimaginable power and utter unnerving and disturbing strangeness. This was a violation and deconstruction of everything I knew about reality, this was ominous and foreboding, I feared I had broken into the nether, and I would end up like so many explorers, dead and gone in the depths of the unknown. It’s unnerving to think you have shattered your reality and gone to a difference plane, one you may never return from. More thoughts on this are in the piece mentioned/linked in the last paragraph of the report. Hope I didn’t sound too narcissistic and pretentious throughout this piece. Sorry for it being so long.

Obscure and Unknown: CNS 5161

*WARNING* The substances mentioned in this series have little to no record of human use, and thus the effects they have on humans are either poorly understood or entirely unknown. Much of what this information is simply hypotheses based on animal trials or very small human sample sizes. Very little information exists about their acute or long-term toxicity. Under no circumstances should any of these substances be ingested by a human outside of a clinical setting where psychological and physiological effects can be closely monitored and extremely precise doses can be prepared and TITRATED. DO NOT seek any of these out if you do not have access to those resources.


I suppose I will start a series prefaced by "New Frontiers", to ramble about potential hallucinogens that I've dug up in medical literature...
The diversity of hallucinogenic drugs can be paralleled with the diversity of animals, as in there is a bottomless boundless quantification of this diversity. There are potentially millions of undiscovered animal species. Not only that, but in the depths of the ocean there could be entire undiscovered phyla, evolutionary lineages and divergences the likes of which we cannot imagine !
Similarly, there could be entirely undiscovered classes of hallucinogenic drug. Within the boundaries of what we know, there could be psychedelics, dissociatives, and deliriants with structures vastly different from the ones we know-entirely new molecular families of substances! Perhaps this can be predicted to a degree by seeing what sorta molecules activate what sorta receptors (how do phenethylamines and tryptamines hit the same receptors???), but there is a boundless frontier to be explored! There could be entirely new classes of hallucinogens beyond the psychedelic-dissociative-deliriant trifecta, entirely new mental states that we cannot possibly comprehend. Some drugs such as glaucine, ibogaine, and muscimol seem to hint at this, being described as unique combinations of the other sorts of hallucinogens. Boundless!
I'm trying to read up on the potential dissociatives that may be arising. My search mostly consists of examining NMDA antagonists, and checking the "adverse effects" section for mentions of delusions, derealization, dissociation, numbness, etc.
*Also wow, this is as amateur as it can get, this is done with the most limited knowledge of pharmacology, neuroscience, neurology, and anything, so like, take this all with a grain of salt, I may very well just have no idea what I'm talking about and be spreading misinformation*

Without further ado, here is the first one I stumbled upon:

CNS 5161

http://chem.sis.nlm.nih.gov/chemidplus/structure/160754-76-7

CNS 5161 is a novel drug currently in the clinical trial stage for the treatment of neuropathic pain. Some dissociatives NMDA antagonists have a history of being used medically for this purpose, such as ketamine. A clinical trial1 provides the following "adverse effects": dysaesthesia, numbness, lightheadedness, derealization, drowsiness, and dizziness. These effects were described as mild. Doses were provided intravenously up to 2 mg. As stated in the conclusion however, "They do not represent a significant psychoactive effect of CNS 5161 within the dose range studied"1 However, thee described effects are reminiscent of threshold-low dose of familiar recreational dissociatives. Another paper seems to corroborate this, opening with:

"Despite encouraging effects of N-methyl-D-aspartate (NMDA) receptor antagonists in reducing neuropathic pain of different aetiologies, the clinical use of these agents has been limited by their mainly psychotropic side-effects."2
"In patients with neuropathic pain CNS 5161 is well tolerated up to a dosage of 500 µg with the most common side-effect of increasing blood pressure, mild visual disturbances and headaches."2
So what we see here is potentially an incredibly potent dissociative, highly active at ranges of 500-2000 ug. The nature of these specific psychoactive effects is unfortunately poorly described and the test subjects likely had little experience with relating or describing such effects. 

On a note of caution, 

"Prominent cardiovascular effects were seen at doses of 1 mg and above. A 15–20% increase in mean arterial pressure was apparent"1

"Some dose-dependent mortality was seen in the animal groups treated with CNS 5161, up to 25% in the highest dose group. These deaths appeared to be related to sudden respiratory failure after continuing i.v. drug infusion under anaesthesia without the assistance of mechanical ventilation."1

(anyone who can locate "Zhou D, Wang S, Hu L, et al. Neuroprotective effect of CNS 5161, a potent NMDA ion-channel antagonist, after focal cerebral ischaemia in rats. Soc for Neuroscience. 1997;23:2433. (946.2)" may be able to find out more about this...)

"Whilst the results of this study are encouraging for continued clinical development of CNS 5161, a cautious approach to the use of similar doses in patients will be necessary."1

(check this out: http://onlinelibrary.wiley.com/doi/10.1002/jlcr.1033/abstract)

Sources and further reading:

1-Walters, M. R., Bradford, A. P., Fischer, J., & Lees, K. R. (2002). Early clinical experience with the novel NMDA receptor antagonist CNS 5161. British journal of clinical pharmacology, 53(3), 305–311. 

2-Forst, T., Smith, T., Schütte, K., Marcus, P., Pfützner, A., & CNS 5161 Study Group (2007). Dose escalating safety study of CNS 5161 HCl, a new neuronal glutamate receptor antagonist (NMDA) for the treatment of neuropathic pain. British journal of clinical pharmacology, 64(1), 75–82
3-Zhao, Y., Robins, E., Turton, D., Brady, F., Luthra, S.K. and Årstad, E. (2006), Synthesis and characterization of N‐(2‐chloro‐5‐methylthiophenyl)‐N′‐(3‐methylthiophenyl)‐N′‐[11C]methylguanidine [11C]CNS 5161, a candidate PET tracer for functional imaging of NMDA receptors. J Label Compd Radiopharm, 49: 163-170. 

4-Zhou D, Wang S, Hu L, et al. Neuroprotective effect of CNS 5161, a potent NMDA ion-channel antagonist, after focal cerebral ischaemia in rats. Soc for Neuroscience. 1997;23:2433.